Research workbench
SSEK1 mutant - F187A
Analyse SSEK1 mutant - F187A in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6IXK
- Type
- protein
- Length
- 578 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Type III secretion system effector protein
- UniProt
- A0A0H3NK84
- Pockets
- 6 · best druggability 0.75
Structure
x-ray diffraction · 2 distinct chains · 39% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Type III secretion system effector protein | protein | 293 | 39% helix, 23% strand | A0A0H3NK84 |
| B | Type III secretion system effector protein | protein | 285 | 39% helix, 19% strand | A0A0H3NK84 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 936 | 0.75 | 0.78 | 74 | empty |
| 2 | 487 | 0.66 | 0.77 | 43 | empty |
| 3 | 109 | 0.40 | 0.76 | 20 | empty |
| 4 | 60 | 0.40 | 0.80 | 12 | empty |
| 5 | 97 | 0.38 | 0.75 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 517 Ų buried · 7 hydrogen bonds · protein-protein
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0H3NK84
- Elsewhere: RCSB PDB 6IXK · PDBe 6IXK · UniProt A0A0H3NK84
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