Research workbench
Type VI secretion system membrane core complex
Analyse Type VI secretion system membrane core complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6IXH
- Type
- protein
- Length
- 6,785 residues
- Chains
- 25
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Type VI secretion system tssj; Type VI secretion system tssm
- UniProt
- B7LFS8, B7LFU0
- Pockets
- 20 · best druggability 0.84
Structure
electron microscopy · 5 distinct chains · 27% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E | Type VI secretion system tssj | protein | 135 | 11% helix, 37% strand | B7LFS8 |
| F, G, H, I, J | Type VI secretion system tssj | protein | 133 | 11% helix, 41% strand | B7LFS8 |
| K, L, M, N, O | Type VI secretion system tssj | protein | 123 | 6% helix, 41% strand | B7LFS8 |
| P, Q, R, S, T | Type VI secretion system tssm | protein | 485 | 33% helix, 13% strand | B7LFU0 |
| U, V, W, X, Y | Type VI secretion system tssm | protein | 481 | 34% helix, 14% strand | B7LFU0 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1127 | 0.84 | 0.85 | 106 | empty |
| 2 | 1038 | 0.84 | 0.85 | 91 | empty |
| 3 | 1088 | 0.84 | 0.85 | 108 | empty |
| 4 | 1044 | 0.84 | 0.85 | 91 | empty |
| 5 | 1005 | 0.84 | 0.85 | 91 | empty |
Interfaces
55 interfaces between chains.
- Q–R · 1751 Ų buried · 16 hydrogen bonds · protein-protein
- R–S · 1747 Ų buried · 13 hydrogen bonds · protein-protein
- S–T · 1744 Ų buried · 14 hydrogen bonds · protein-protein
- P–T · 1744 Ų buried · 18 hydrogen bonds · protein-protein
- P–Q · 1737 Ų buried · 16 hydrogen bonds · protein-protein
Compared structures
- 6IXH · Type VI secretion system membrane core complex · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B7LFS8
- Every structure of UniProt B7LFU0
- Elsewhere: RCSB PDB 6IXH · PDBe 6IXH · UniProt B7LFS8 · UniProt B7LFU0
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.