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The full length of tgev NSP1

Analyse The full length of tgev NSP1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6IVC
Type: protein
Length: 433 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: NSP1 protein
UniProt: A0A140EDJ9
Pockets: 6 · best druggability 0.46

Structure

x-ray diffraction · 4 distinct chains · 18% helix, 43% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	NSP1 protein	protein	105	19% helix, 44% strand	A0A140EDJ9
B	NSP1 protein	protein	110	18% helix, 42% strand	A0A140EDJ9
E	NSP1 protein	protein	104	19% helix, 45% strand	A0A140EDJ9
F	NSP1 protein	protein	114	18% helix, 42% strand	A0A140EDJ9

Pockets

6 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	166	0.46	0.76	27	empty
2	164	0.43	0.74	27	empty
3	138	0.43	0.75	27	empty
4	120	0.41	0.75	26	empty
5	85	0.39	0.77	19	empty

Interfaces

3 interfaces between chains.

B–E · 410 Å² buried · 7 hydrogen bonds · protein-protein
E–F · 266 Å² buried · 6 hydrogen bonds · protein-protein
A–B · 181 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

6IVC · The full length of TGEV nsp1 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A140EDJ9
Elsewhere: RCSB PDB 6IVC · PDBe 6IVC · UniProt A0A140EDJ9

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