Research workbench
X-ray structure of sufe from E.COLI northeast structural genomics (nesg) consortium target ER30
Analyse X-ray structure of sufe from E.COLI northeast structural genomics (nesg)… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1MZG
- Type
- protein
- Length
- 287 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sufe protein
- UniProt
- P76194
- Pockets
- 3 · best druggability 0.41
Structure
x-ray diffraction · 2 distinct chains · 53% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sufe protein | protein | 144 | 57% helix, 11% strand | P76194 |
| B | Sufe protein | protein | 143 | 49% helix, 11% strand | P76194 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 79 | 0.41 | 0.79 | 17 | empty |
| 2 | 121 | 0.40 | 0.75 | 20 | empty |
| 3 | 57 | 0.30 | 0.75 | 12 | empty |
Interfaces
1 interface between chains.
- A–B · 486 Ų buried · 12 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 8 modified (engineered).
Compared structures
- 1MZG · X-Ray Structure of SufE from E.coli Northeast Structural Genomics (NESG) Consortium… · the same entry in another collection · chain A against A, TM-score 1.00
- P76194 · AlphaFold monomer V2.0 prediction for cysteine desulfuration protein sufe (P76194) · a predicted model of the same protein · chain B against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P76194
- Elsewhere: RCSB PDB 1MZG · PDBe 1MZG · UniProt P76194
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