Research workbench
The crystal structure of ASFVLIG:CT1 complex
Analyse The crystal structure of ASFVLIG:CT1 complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6IML
- Type
- protein + DNA
- Length
- 447 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DNA ligase; DNA (5'- D(*CP*CP*AP*GP*TP*CP*CP*GP*AP*CP*CP*CP*GP*CP*AP*TP*CP*CP*CP*GP*GP*A)…
- UniProt
- A0A0A1E0U0
- Pockets
- 5 · best druggability 0.83
Structure
x-ray diffraction · 4 distinct chains · 24% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA ligase | protein | 403 | 24% helix, 33% strand | A0A0A1E0U0 |
| C | DNA (5'- D(*CP*CP*AP*GP*TP*CP*CP*GP*AP*CP*CP*CP*GP*CP*AP*TP*CP*CP*CP*GP*GP*A)- 3') | dna | 22 | — | — |
| D | DNA (5'-D(*TP*CP*CP*GP*GP*GP*AP*TP*GP*CP*GP*T)-3') | dna | 12 | — | — |
| E | DNA (5'-D(P*GP*TP*CP*GP*GP*AP*CP*TP*GP*G)-3') | dna | 10 | — | — |
Pockets
5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1172 | 0.83 | 0.85 | 78 | empty |
| 2 | 72 | 0.72 | 0.97 | 22 | empty |
| 3 | 142 | 0.59 | 0.84 | 16 | empty |
| 4 | 219 | 0.54 | 0.78 | 28 | empty |
| 5 | 142 | 0.47 | 0.77 | 19 | empty |
Interfaces
6 interfaces between chains.
- A–C · 1334 Ų buried · 23 hydrogen bonds · protein-nucleic
- A–E · 657 Ų buried · 12 hydrogen bonds · protein-nucleic
- A–D · 609 Ų buried · 17 hydrogen bonds · protein-nucleic
- C–D · 542 Ų buried · 62 hydrogen bonds · nucleic-nucleic
- C–E · 527 Ų buried · 53 hydrogen bonds · nucleic-nucleic
Compared structures
- 6IML · The crystal structure of AsfvLIG:CT1 complex · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0A1E0U0
- Elsewhere: RCSB PDB 6IML · PDBe 6IML · UniProt A0A0A1E0U0
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.