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Solution structure of the water-soluble lu-domain of human LYPD6 protein

Analyse Solution structure of the water-soluble lu-domain of human LYPD6 protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6IB6
Type: protein
Length: 96 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: LY6/PLAUR domain-containing protein 6
UniProt: Q86Y78
Pockets: 1 · best druggability 0.57

Structure

solution nmr · 1 distinct chain · 7% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	LY6/PLAUR domain-containing protein 6	protein	96	7% helix, 26% strand	Q86Y78

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	246	0.57	0.78	35	empty

Modifications

Observed in the structure: 6 disulfide (disulfide).

Compared structures

6IB6 · Solution structure of the water-soluble LU-domain of human Lypd6 protein · the same entry in another collection · chain A against A, TM-score 1.00
Q86Y78 · AlphaFold monomer V2.0 prediction for LY6/PLAUR domain-containing protein 6 (Q86Y78) · a predicted model of the same protein · chain A against A, TM-score 0.72

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q86Y78
Elsewhere: RCSB PDB 6IB6 · PDBe 6IB6 · UniProt Q86Y78

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