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Structure of head fiber and inner core protein GP22 of native bacteriophage P68

Analyse Structure of head fiber and inner core protein GP22 of native bacteriophage P68 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6IAW
Type: protein
Length: 2,789 residues
Chains: 18
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Major head protein; Arstotzka protein; Head fiber; Inner core protein
UniProt: Q859I3, Q859I2
Pockets: 20 · best druggability 0.82

Structure

electron microscopy · 10 distinct chains · 22% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Major head protein	protein	393	23% helix, 22% strand	Q859I3
B, C, N, O	Major head protein	protein	386	24% helix, 22% strand	Q859I3
J, I, Q, S	Arstotzka protein	protein	55	0% helix, 2% strand	Q859I2
D	Arstotzka protein	protein	30	0% helix, 0% strand	Q859I2
E	Arstotzka protein	protein	54	6% helix, 2% strand	Q859I2
H, L, K	Head fiber	protein	55	25% helix, 15% strand	—
M	Major head protein	protein	338	26% helix, 25% strand	Q859I3
X	Inner core protein	protein	17	41% helix, 6% strand	—
Y	Inner core protein	protein	16	0% helix, 0% strand	—
Z	Inner core protein	protein	12	0% helix, 0% strand	—

Pockets

20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	403	0.82	0.91	71	empty
2	919	0.81	0.82	114	empty
3	962	0.80	0.81	94	empty
4	242	0.77	0.90	46	empty
5	679	0.76	0.81	71	empty

Interfaces

68 interfaces between chains.

A–C · 3090 Å² buried · 44 hydrogen bonds · protein-protein
M–O · 3051 Å² buried · 40 hydrogen bonds · protein-protein
B–O · 3034 Å² buried · 36 hydrogen bonds · protein-protein
C–N · 2984 Å² buried · 30 hydrogen bonds · protein-protein
A–B · 2982 Å² buried · 37 hydrogen bonds · protein-protein

Compared structures

6IAW · Structure of head fiber and inner core protein gp22 of native bacteriophage P68 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q859I3
Every structure of UniProt Q859I2
Elsewhere: RCSB PDB 6IAW · PDBe 6IAW · UniProt Q859I3 · UniProt Q859I2

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