Research workbench
Circular permutant of ribosomal protein S6, adding 6AA to C terminal of P68-69, L75A mutant
Analyse Circular permutant of ribosomal protein S6, adding 6AA to C terminal of P68-69… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6I6I
- Type
- protein
- Length
- 192 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 30S ribosomal protein S6,30S ribosomal protein S6
- UniProt
- Q5SLP8, P62666
- Ligands
- SO4
- Pockets
- 2 · best druggability 0.41
Structure
x-ray diffraction · 1 distinct chain · 29% helix, 40% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | 30S ribosomal protein S6,30S ribosomal protein S6 | protein | 96 | 29% helix, 40% strand | Q5SLP8, P62666 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 90 | 0.41 | 0.78 | 16 | empty |
| 2 | 90 | 0.36 | 0.75 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 428 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
- 6I6I · Circular permutant of ribosomal protein S6, adding 6aa to C terminal of P68-69, L75A… · the same entry in another collection · chain A against A, TM-score 1.00
- P62666 · AlphaFold monomer V2.0 prediction for 30S ribosomal protein S6 (P62666) · a predicted model of the same protein · chain A against A, TM-score 0.62
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5SLP8
- Every structure of UniProt P62666
- Elsewhere: RCSB PDB 6I6I · PDBe 6I6I · UniProt Q5SLP8 · UniProt P62666
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