Research workbench
Arabidopsis OM64 tpr domain
Analyse Arabidopsis OM64 tpr domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6HPG
- Type
- protein
- Length
- 755 residues
- Chains
- 12
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Outer envelope protein 64, mitochondrial; Heat shock protein 90-4
- UniProt
- F4KCL7, O03986
- Pockets
- 7 · best druggability 0.49
Structure
x-ray diffraction · 4 distinct chains · 75% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, D | Outer envelope protein 64, mitochondrial | protein | 121 | 79% helix, 0% strand | F4KCL7 |
| B, C, E, F | Outer envelope protein 64, mitochondrial | protein | 117 | 81% helix, 0% strand | F4KCL7 |
| a, b, d | Heat shock protein 90-4 | protein | 8 | 0% helix, 0% strand | O03986 |
| c, e, f | Heat shock protein 90-4 | protein | 7 | 0% helix, 0% strand | O03986 |
Pockets
7 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 286 | 0.49 | 0.73 | 35 | empty |
| 2 | 101 | 0.45 | 0.79 | 16 | empty |
| 3 | 183 | 0.44 | 0.74 | 28 | empty |
| 4 | 126 | 0.39 | 0.74 | 16 | empty |
| 5 | 96 | 0.38 | 0.75 | 15 | empty |
Interfaces
14 interfaces between chains.
- A–a · 533 Ų buried · 16 hydrogen bonds · protein-protein
- D–d · 532 Ų buried · 15 hydrogen bonds · protein-protein
- C–c · 525 Ų buried · 13 hydrogen bonds · protein-protein
- F–f · 522 Ų buried · 14 hydrogen bonds · protein-protein
- B–b · 517 Ų buried · 13 hydrogen bonds · protein-protein
Compared structures
- 6HPG · Arabidopsis OM64 TPR domain · the same entry in another collection · chain f against f, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt F4KCL7
- Every structure of UniProt O03986
- Elsewhere: RCSB PDB 6HPG · PDBe 6HPG · UniProt F4KCL7 · UniProt O03986
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