Research workbench
Crystal structure of the hicb antitoxin from E. COLI
Analyse Crystal structure of the hicb antitoxin from E. COLI in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6HPC
- Type
- protein
- Length
- 276 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Antitoxin hicb
- UniProt
- A0A070SL92
- Pockets
- 4 · best druggability 0.53
Structure
x-ray diffraction · 1 distinct chain · 45% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B, A | Antitoxin hicb | protein | 138 | 45% helix, 19% strand | A0A070SL92 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 62 | 0.53 | 0.87 | 19 | empty |
| 2 | 72 | 0.53 | 0.86 | 17 | empty |
| 3 | 126 | 0.42 | 0.76 | 27 | empty |
| 4 | 55 | 0.36 | 0.79 | 13 | empty |
Interfaces
1 interface between chains.
- B–A · 1314 Ų buried · 26 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 8 modified (engineered).
Compared structures
- 6HPC · Crystal structure of the HicB antitoxin from E. coli · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A070SL92
- Elsewhere: RCSB PDB 6HPC · PDBe 6HPC · UniProt A0A070SL92
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