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XI class GST from natrialba magadii

Analyse XI class GST from natrialba magadii in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6GZF
Type: protein
Length: 647 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glutathione S-transferase
EC: 2.5.1.18
UniProt: D3SS28
Ligands: SO4
Pockets: 5 · best druggability 0.74

Structure

x-ray diffraction · 2 distinct chains · 37% helix, 11% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glutathione S-transferase (EC 2.5.1.18)	protein	327	38% helix, 10% strand	D3SS28
B	Glutathione S-transferase (EC 2.5.1.18)	protein	320	36% helix, 12% strand	D3SS28

Ligands and binding sites

SO4 · Sulfate ion · ion · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	279	0.74	0.87	33	empty
2	209	0.72	0.88	34	empty
3	59	0.72	0.98	22	SO4
4	266	0.53	0.76	28	empty
5	55	0.25	0.72	16	empty

Interfaces

1 interface between chains.

A–B · 1347 Å² buried · 25 hydrogen bonds · protein-protein

Compared structures

6GZF · Xi Class GST from Natrialba magadii · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt D3SS28
Elsewhere: RCSB PDB 6GZF · PDBe 6GZF · UniProt D3SS28

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