Research workbench
Major sperm protein, alpha isoform (recombinant), pH 4.6
Analyse Major sperm protein, alpha isoform (recombinant), pH 4.6 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1MSP
- Type
- protein
- Length
- 246 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Major sperm protein
- UniProt
- P27439
- Pockets
- 1 · best druggability 0.53
Structure
x-ray diffraction · 2 distinct chains · 4% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Major sperm protein | protein | 124 | 6% helix, 45% strand | P27439 |
| B | Major sperm protein | protein | 122 | 2% helix, 43% strand | P27439 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 174 | 0.53 | 0.79 | 28 | empty |
Interfaces
1 interface between chains.
- A–B · 663 Ų buried · 16 hydrogen bonds · protein-protein
Compared structures
- 1MSP · Major sperm protein, alpha isoform (recombinant), pH 4.6 · the same entry in another collection · chain A against A, TM-score 1.00
- P27439 · AlphaFold monomer V2.0 prediction for major sperm protein isoform alpha (P27439) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P27439
- Elsewhere: RCSB PDB 1MSP · PDBe 1MSP · UniProt P27439
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