Research workbench
Blood group synthase aaglyb in complex with udp-gal and cryoprotected with peg 3350
Analyse Blood group synthase aaglyb in complex with udp-gal and cryoprotected with peg… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6GX0
- Type
- protein
- Length
- 288 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Abo blood group (transferase a, alpha 1-3-N- acetylgalactosaminyltransferase transferase…
- UniProt
- F0X360
- Ligands
- GDU, MN, SO4
- Pockets
- 1 · best druggability 0.63
Structure
x-ray diffraction · 1 distinct chain · 33% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Abo blood group (transferase a, alpha 1-3-N- acetylgalactosaminyltransferase transferase B, alpha 1-3- galactosyltransferase) | protein | 288 | 33% helix, 19% strand | F0X360 |
Ligands and binding sites
- GDU · Galactose-uridine-5'-diphosphate · ligand · chains A
- MN · Manganese (II) ion · metal · chains A
- SO4 · Sulfate ion · ion · 3 copies · chains A
- EDO · 1,2-ethanediol · additive · 3 copies · chains A
- PEG · Di(hydroxyethyl)ether · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 349 | 0.63 | 0.78 | 33 | MN, GDU |
Compared structures
- 6GX0 · Blood group synthase AAGlyB in complex with UDP-Gal and cryoprotected with PEG 3350 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt F0X360
- Elsewhere: RCSB PDB 6GX0 · PDBe 6GX0 · UniProt F0X360
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