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Tc-DNA/TC-DNA duplex

Analyse Tc-DNA/TC-DNA duplex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
6GN4
Type
DNA
Length
20 nucleotides
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Tc-DNA (5'-D(*(TCJ)P*(TTK)P*(TCJ)P*(TCS)P*(TCS)P*(TCJ) P*(TTK)P*(TTK)P*(TCY)P*(TCJ))-3')

Structure

solution nmr · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
A, BTc-DNA (5'-D(*(TCJ)P*(TTK)P*(TCJ)P*(TCS)P*(TCS)P*(TCJ) P*(TTK)P*(TTK)P*(TCY)P*(TCJ))-3')dna10——

Interfaces

1 interface between chains.

  • A–B · 494 Ų buried · 46 hydrogen bonds · nucleic-nucleic

Modifications

Observed in the structure: 20 modified (nucleotide modification).

Compared structures

  • 6GN4 · tc-DNA/tc-DNA duplex · the same entry in another collection · chain A against A, TM-score 1.00

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