Research workbench
Crystal structure of TACT3 (tRNA acetylating toxin) from salmonella
Analyse Crystal structure of TACT3 (tRNA acetylating toxin) from salmonella in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6G96
- Type
- protein
- Length
- 349 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Acetyltransferase
- UniProt
- A0A0J5HSJ5
- Ligands
- ACO, BCN
- Pockets
- 4 · best druggability 0.71
Structure
x-ray diffraction · 2 distinct chains · 36% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Acetyltransferase | protein | 174 | 34% helix, 33% strand | A0A0J5HSJ5 |
| A | Acetyltransferase | protein | 175 | 37% helix, 27% strand | A0A0J5HSJ5 |
Ligands and binding sites
- ACO · Acetyl coenzyme *A · ligand · 2 copies · chains B, A
- BCN · Bicine · ligand · chains B
- GOL · Glycerol · additive · 2 copies · chains B, A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 737 | 0.71 | 0.77 | 66 | ACO |
| 2 | 459 | 0.66 | 0.78 | 46 | ACO |
| 3 | 137 | 0.42 | 0.74 | 18 | GOL |
| 4 | 58 | 0.27 | 0.74 | 16 | empty |
Interfaces
1 interface between chains.
- B–A · 1109 Ų buried · 12 hydrogen bonds · protein-protein
Compared structures
- 6G96 · Crystal structure of TacT3 (tRNA acetylating toxin) from Salmonella · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0J5HSJ5
- Elsewhere: RCSB PDB 6G96 · PDBe 6G96 · UniProt A0A0J5HSJ5
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