Research workbench
Structure of murine PRPF39
Analyse Structure of murine PRPF39 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6G70
- Type
- protein
- Length
- 1,019 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Pre-mRNA-processing factor 39
- UniProt
- E9QJV4
- Pockets
- 19 · best druggability 0.75
Structure
x-ray diffraction · 2 distinct chains · 78% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pre-mRNA-processing factor 39 | protein | 509 | 78% helix, 0% strand | E9QJV4 |
| B | Pre-mRNA-processing factor 39 | protein | 510 | 78% helix, 0% strand | E9QJV4 |
Pockets
19 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 744 | 0.75 | 0.80 | 53 | empty |
| 2 | 330 | 0.59 | 0.76 | 30 | empty |
| 3 | 86 | 0.53 | 0.84 | 16 | empty |
| 4 | 91 | 0.53 | 0.84 | 16 | empty |
| 5 | 148 | 0.51 | 0.78 | 19 | empty |
Interfaces
1 interface between chains.
- A–B · 1674 Ų buried · 32 hydrogen bonds · protein-protein
Compared structures
- 6G70 · Structure of murine Prpf39 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt E9QJV4
- Elsewhere: RCSB PDB 6G70 · PDBe 6G70 · UniProt E9QJV4
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