Research workbench
Crystal structure of substrate binding domain 1 (SBD1) of ABC transporter glnpq in complex with asparagine
Analyse Crystal structure of substrate binding domain 1 (SBD1) of ABC transporter glnpq… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6FXG
- Type
- protein
- Length
- 675 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Amino acid ABC transporter membrane protein paat family
- UniProt
- A0A1V0NHP2
- Ligands
- ASN
- Pockets
- 9 · best druggability 0.74
Structure
x-ray diffraction · 3 distinct chains · 38% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Amino acid ABC transporter membrane protein paat family | protein | 225 | 38% helix, 26% strand | A0A1V0NHP2 |
| B | Amino acid ABC transporter membrane protein paat family | protein | 226 | 38% helix, 26% strand | A0A1V0NHP2 |
| C | Amino acid ABC transporter membrane protein paat family | protein | 224 | 38% helix, 26% strand | A0A1V0NHP2 |
Ligands and binding sites
- ASN · Asparagine · ligand · 3 copies · chains A, B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
9 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 977 | 0.74 | 0.77 | 81 | empty |
| 2 | 237 | 0.53 | 0.76 | 26 | empty |
| 3 | 79 | 0.45 | 0.81 | 17 | empty |
| 4 | 62 | 0.44 | 0.82 | 16 | empty |
| 5 | 107 | 0.39 | 0.76 | 25 | empty |
Interfaces
2 interfaces between chains.
- A–B · 539 Ų buried · 7 hydrogen bonds · protein-protein
- B–C · 382 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 6FXG · Crystal structure of substrate binding domain 1 (SBD1) OF ABC transporter GLNPQ in… · the same entry in another collection · chain C against C, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A1V0NHP2
- Elsewhere: RCSB PDB 6FXG · PDBe 6FXG · UniProt A0A1V0NHP2
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