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Mitf dimerization mutant

Analyse Mitf dimerization mutant in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6FX5
Type: protein
Length: 146 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Microphthalmia-associated transcription factor
UniProt: Q08874
Ligands: SO4

Structure

x-ray diffraction · 2 distinct chains · 81% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Microphthalmia-associated transcription factor	protein	72	81% helix, 0% strand	Q08874
B	Microphthalmia-associated transcription factor	protein	74	81% helix, 0% strand	Q08874

Ligands and binding sites

SO4 · Sulfate ion · ion · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 1749 Å² buried · 12 hydrogen bonds · protein-protein

Compared structures

6FX5 · MITF dimerization mutant · the same entry in another collection · chain A against A, TM-score 1.00
Q08874 · AlphaFold monomer V2.0 prediction for microphthalmia-associated transcription factor… · a predicted model of the same protein · chain B against A, TM-score 0.81

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q08874
Elsewhere: RCSB PDB 6FX5 · PDBe 6FX5 · UniProt Q08874

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