Research workbench
Thioester domain of the enterococcus faecium TIE86 protein
Analyse Thioester domain of the enterococcus faecium TIE86 protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6FWY
- Type
- protein
- Length
- 1,118 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- B-type cna protein
- UniProt
- A0A1A7T0E1
- Pockets
- 7 · best druggability 0.69
Structure
x-ray diffraction · 2 distinct chains · 20% helix, 45% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | B-type cna protein | protein | 280 | 20% helix, 45% strand | A0A1A7T0E1 |
| C, D | B-type cna protein | protein | 279 | 20% helix, 44% strand | A0A1A7T0E1 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 723 | 0.69 | 0.76 | 72 | empty |
| 2 | 277 | 0.53 | 0.76 | 35 | empty |
| 3 | 60 | 0.31 | 0.75 | 15 | empty |
| 4 | 59 | 0.30 | 0.75 | 17 | empty |
| 5 | 52 | 0.28 | 0.75 | 15 | empty |
Interfaces
3 interfaces between chains.
- A–C · 376 Ų buried · 4 hydrogen bonds · protein-protein
- B–C · 255 Ų buried · 3 hydrogen bonds · protein-protein
- A–B · 20 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 6FWY · Thioester domain of the Enterococcus faecium TIE86 protein · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A1A7T0E1
- Elsewhere: RCSB PDB 6FWY · PDBe 6FWY · UniProt A0A1A7T0E1
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