Research workbench
Periplasmic coiled coil domain of the fapf amyloid transporter
Analyse Periplasmic coiled coil domain of the fapf amyloid transporter in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6FUE
- Type
- protein
- Length
- 223 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fapf
- UniProt
- C4IN73
- Ligands
- ZN, NA
- Pockets
- 1 · best druggability 0.71
Structure
x-ray diffraction · 4 distinct chains · 90% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | Fapf | protein | 38 | 87% helix, 0% strand | C4IN73 |
| D | Fapf | protein | 36 | 94% helix, 0% strand | C4IN73 |
| E | Fapf | protein | 36 | 92% helix, 0% strand | C4IN73 |
| F | Fapf | protein | 37 | 89% helix, 0% strand | C4IN73 |
Ligands and binding sites
- ZN · Zinc ion · metal · 11 copies · chains A, D, B, E, C, F
- NA · Sodium ion · metal · 6 copies · chains B, D, F
- IPA · Isopropyl alcohol · additive · chains C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 667 | 0.71 | 0.78 | 48 | empty |
Interfaces
9 interfaces between chains.
- A–C · 788 Ų buried · 7 hydrogen bonds · protein-protein
- D–E · 783 Ų buried · 6 hydrogen bonds · protein-protein
- A–B · 770 Ų buried · 5 hydrogen bonds · protein-protein
- E–F · 745 Ų buried · 5 hydrogen bonds · protein-protein
- B–C · 712 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 6FUE · Periplasmic coiled coil domain of the FapF amyloid transporter · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C4IN73
- Elsewhere: RCSB PDB 6FUE · PDBe 6FUE · UniProt C4IN73
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.