Research workbench
Crystal structure of anti-MTFP1 darpin 1238_E11
Analyse Crystal structure of anti-MTFP1 darpin 1238_E11 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6FP9
- Type
- protein
- Length
- 334 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Darpin 1238_E11
- Ligands
- SO4
- Pockets
- 3 · best druggability 0.70
Structure
x-ray diffraction · 2 distinct chains · 55% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Darpin 1238_E11 | protein | 163 | 57% helix, 0% strand | — |
| A | Darpin 1238_E11 | protein | 171 | 54% helix, 0% strand | — |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 337 | 0.70 | 0.83 | 42 | EDO |
| 2 | 181 | 0.45 | 0.75 | 24 | SO4 |
| 3 | 68 | 0.30 | 0.73 | 13 | EDO |
Interfaces
1 interface between chains.
- B–A · 606 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
- 6FP9 · Crystal structure of anti-mTFP1 DARPin 1238_E11 · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6FP9 · PDBe 6FP9
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