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Structure of moloney murine leukaemia virus matrix protein
Analyse Structure of moloney murine leukaemia virus matrix protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1MN8
- Type
- protein
- Length
- 379 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Core protein P15
- UniProt
- P03332
- Pockets
- 2 · best druggability 0.67
Structure
x-ray diffraction · 4 distinct chains · 63% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Core protein P15 | protein | 95 | 61% helix, 0% strand | P03332 |
| B | Core protein P15 | protein | 93 | 62% helix, 0% strand | P03332 |
| C | Core protein P15 | protein | 94 | 65% helix, 0% strand | P03332 |
| D | Core protein P15 | protein | 97 | 63% helix, 0% strand | P03332 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 497 | 0.67 | 0.78 | 46 | empty |
| 2 | 64 | 0.28 | 0.73 | 11 | empty |
Interfaces
5 interfaces between chains.
- A–D · 620 Ų buried · 8 hydrogen bonds · protein-protein
- A–B · 595 Ų buried · 11 hydrogen bonds · protein-protein
- B–C · 476 Ų buried · 9 hydrogen bonds · protein-protein
- C–D · 265 Ų buried · 5 hydrogen bonds · protein-protein
- A–C · 63 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 1MN8 · Structure of Moloney Murine Leukaemia Virus Matrix Protein · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03332
- Elsewhere: RCSB PDB 1MN8 · PDBe 1MN8 · UniProt P03332
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