Research workbench
Crystal structure of a tailored I-crei homing endonuclease protein (3115 variant) in complex with an altered version of its target DNA (haemoglobin beta subunit gene) at 5NNN region in the presence of magnesium
Analyse Crystal structure of a tailored I-crei homing endonuclease protein (3115… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6FB5
- Type
- protein + DNA
- Length
- 355 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Ligands
- MG
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 153 | — | — |
| B | — | protein | 154 | — | — |
| D | — | dna | 24 | — | — |
| F | — | dna | 24 | — | — |
Ligands and binding sites
- MG · Magnesium ion · metal · 4 copies · chains A, B, D, F
- ACT · Acetate ion · additive · chains A, B
- PGO · S-1,2-propanediol · additive · chains A, B, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6FB5 · Crystal Structure of a Tailored I-CreI Homing Endonuclease Protein (3115 variant) in… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6FB5 · PDBe 6FB5
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.