Research workbench
The crystal structure of an all-RNA hammerhead ribozyme: a proposed mechanism for RNA catalytic cleavage
Analyse The crystal structure of an all-RNA hammerhead ribozyme: a proposed mechanism… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1MME
- Type
- RNA
- Length
- 82 nucleotides
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RNA hammerhead ribozyme
- Pockets
- 1 · best druggability 0.28
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C | RNA hammerhead ribozyme | rna | 16 | — | — |
| B, D | RNA hammerhead ribozyme | rna | 25 | — | — |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 70 | 0.28 | 0.74 | 11 | empty |
Interfaces
6 interfaces between chains.
- C–D · 1037 Ų buried · 86 hydrogen bonds · nucleic-nucleic
- A–B · 1028 Ų buried · 78 hydrogen bonds · nucleic-nucleic
- A–D · 227 Ų buried · 6 hydrogen bonds · nucleic-nucleic
- B–C · 222 Ų buried · 4 hydrogen bonds · nucleic-nucleic
- A–C · 71 Ų buried · 0 hydrogen bonds · nucleic-nucleic
Compared structures
- 1MME · The crystal structure of an all-RNA hammerhead ribozyme: a proposed mechanism for RNA… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1MME · PDBe 1MME
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