Research workbench
Structure of the neurospora set domain protein dim-5, a histone lysine methyltransferase
Analyse Structure of the neurospora set domain protein dim-5, a histone lysine… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1ML9
- Type
- protein
- Length
- 260 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Histone H3 methyltransferase dim-5
- EC
- 2.1.1.43
- Ligands
- ZN, UNK
- Pockets
- 3 · best druggability 0.54
Structure
x-ray diffraction · 1 distinct chain · 19% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Histone H3 methyltransferase dim-5 (EC 2.1.1.43) | protein | 260 | 19% helix, 23% strand | — |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 275 | 0.54 | 0.76 | 39 | UNK |
| 2 | 143 | 0.44 | 0.76 | 21 | empty |
| 3 | 142 | 0.42 | 0.75 | 22 | empty |
Compared structures
- 1ML9 · Structure of the Neurospora SET domain protein DIM-5, a histone lysine methyltransferase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1ML9 · PDBe 1ML9
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