Research workbench
MDFA(Q131R/L339E)
Analyse MDFA(Q131R/L339E) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6EUQ
- Type
- protein
- Length
- 386 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Multidrug transporter mdfa
- UniProt
- P0AEY8
- Ligands
- BNG, DXC, PR
- Pockets
- 1 · best druggability 0.82
Structure
x-ray diffraction · 1 distinct chain · 85% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Multidrug transporter mdfa | protein | 386 | 85% helix, 0% strand | P0AEY8 |
Ligands and binding sites
- BNG · nonyl beta-D-glucopyranoside · ligand · chains A
- DXC · (3alpha,5beta,12alpha)-3,12-dihydroxycholan-24-oic acid · ligand · chains A
- PR · Praseodymium ion · metal · 2 copies · chains A
- PGE · Triethylene glycol · additive · 3 copies · chains A
- OCT · N-octane · additive · 3 copies · chains A
- HEX · Hexane · additive · chains A
- ACT · Acetate ion · additive · chains A
- PG4 · Tetraethylene glycol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1118 | 0.82 | 0.83 | 64 | DXC, PGE, ACT |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0AEY8
- Elsewhere: RCSB PDB 6EUQ · PDBe 6EUQ · UniProt P0AEY8
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