GL1X · GenesisL1 explorer

Research workbench

The crystal structure of mouse chloride intracellular channel protein 6

Analyse The crystal structure of mouse chloride intracellular channel protein 6 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
6ERY
Type
protein
Length
464 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Chloride intracellular channel protein 6
UniProt
Q8BHB9
Ligands
SO4
Pockets
1 · best druggability 0.74

Structure

x-ray diffraction · 2 distinct chains · 48% helix, 10% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
BChloride intracellular channel protein 6protein23047% helix, 9% strandQ8BHB9
AChloride intracellular channel protein 6protein23449% helix, 10% strandQ8BHB9

Ligands and binding sites

  • SO4 · Sulfate ion · ion · 3 copies · chains B, A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
17580.740.7965SO4

Interfaces

1 interface between chains.

  • B–A · 474 Ų buried · 6 hydrogen bonds · protein-protein

Compared structures

  • 6ERY · The crystal structure of mouse chloride intracellular channel protein 6 · the same entry in another collection · chain B against B, TM-score 1.00
  • Q8BHB9 · AlphaFold monomer V2.0 prediction for chloride intracellular channel protein 6 (Q8BHB9) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.