Research workbench
Carbon monoxide dehydrogenase IV from carboxydothermus hydrogenoformans
Analyse Carbon monoxide dehydrogenase IV from carboxydothermus hydrogenoformans in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6ELQ
- Type
- protein
- Length
- 1,890 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Carbon monoxide dehydrogenase
- EC
- 1.2.7.4
- UniProt
- Q3AE44
- Ligands
- SF4, BF8
- Pockets
- 18 · best druggability 0.83
Structure
x-ray diffraction · 1 distinct chain · 52% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| X, A, B | Carbon monoxide dehydrogenase (EC 1.2.7.4) | protein | 630 | 52% helix, 10% strand | Q3AE44 |
Ligands and binding sites
- SF4 · Iron/sulfur cluster · ligand · 5 copies · chains X, A, B
- BF8 · FE(4)-NI(1)-S(5) CLUSTER with Oxygen · ligand · 3 copies · chains X, A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
18 pockets found on a 1 Å grid, 11 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 174 | 0.83 | 0.97 | 61 | BF8 |
| 2 | 194 | 0.83 | 0.96 | 57 | BF8 |
| 3 | 149 | 0.79 | 0.95 | 46 | empty |
| 4 | 147 | 0.79 | 0.96 | 32 | SF4 |
| 5 | 87 | 0.72 | 0.95 | 31 | empty |
Interfaces
3 interfaces between chains.
- X–A · 3758 Ų buried · 79 hydrogen bonds · protein-protein
- A–B · 143 Ų buried · 5 hydrogen bonds · protein-protein
- X–B · 20 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 6ELQ · Carbon Monoxide Dehydrogenase IV from Carboxydothermus hydrogenoformans · the same entry in another collection · chain X against X, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q3AE44
- Elsewhere: RCSB PDB 6ELQ · PDBe 6ELQ · UniProt Q3AE44
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.