Research workbench
Scfv abvance: increasing our knowledge of antibody structural space to enable faster and better decision making in drug discovery
Analyse Scfv abvance: increasing our knowledge of antibody structural space to enable… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6EHW
- Type
- protein
- Length
- 237 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Scfv abvance: increasing our knowledge of antibody structural space to enable faster and…
- Pockets
- 2 · best druggability 0.39
Structure
x-ray diffraction · 1 distinct chain · 4% helix, 47% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Scfv abvance: increasing our knowledge of antibody structural space to enable faster and better decision making in drug discovery | protein | 237 | 4% helix, 47% strand | — |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 117 | 0.39 | 0.75 | 29 | empty |
| 2 | 51 | 0.24 | 0.73 | 11 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 6EHW · scFv AbVance: increasing our knowledge of antibody structural space to enable faster and… · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6EHW · PDBe 6EHW
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