Research workbench
Crystal structure of leishmania braziliensis glucokinase
Analyse Crystal structure of leishmania braziliensis glucokinase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6EDI
- Type
- protein
- Length
- 788 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glucokinase
- EC
- 2.7.1.2
- UniProt
- A4HPA0
- Pockets
- 8 · best druggability 0.83
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Glucokinase (EC 2.7.1.2) | protein | 394 | 43% helix, 23% strand | A4HPA0 |
Pockets
8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1188 | 0.83 | 0.84 | 151 | empty |
| 2 | 194 | 0.65 | 0.85 | 29 | empty |
| 3 | 159 | 0.64 | 0.86 | 28 | empty |
| 4 | 398 | 0.59 | 0.76 | 44 | empty |
| 5 | 50 | 0.36 | 0.80 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 2378 Ų buried · 23 hydrogen bonds · protein-protein
Compared structures
- 6EDI · Crystal structure of Leishmania braziliensis glucokinase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A4HPA0
- Elsewhere: RCSB PDB 6EDI · PDBe 6EDI · UniProt A4HPA0
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