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DHF79 filament

Analyse DHF79 filament in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
6E9V
Type
protein
Length
5,486 residues
Chains
26
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
DHF79 filament
Pockets
20 · best druggability 0.70

Structure

electron microscopy · 1 distinct chain · 88% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
Q, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, R, S, T, U, V, W, X, Y, ZDHF79 filamentprotein21188% helix, 0% strand—

Pockets

20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
19200.700.7578empty
28830.700.7579empty
38330.700.7681empty
47710.690.7667empty
57240.690.7666empty

Interfaces

43 interfaces between chains.

  • A–E · 375 Ų buried · 4 hydrogen bonds · protein-protein
  • O–T · 374 Ų buried · 4 hydrogen bonds · protein-protein
  • E–I · 374 Ų buried · 4 hydrogen bonds · protein-protein
  • H–L · 373 Ų buried · 4 hydrogen bonds · protein-protein
  • S–W · 373 Ų buried · 4 hydrogen bonds · protein-protein

Compared structures

  • 6E9V · DHF79 filament · the same entry in another collection · chain I against I, TM-score 1.00

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