Research workbench
Mper-tm domain of HIV-1 envelope glycoprotein (env)
Analyse Mper-tm domain of HIV-1 envelope glycoprotein (env) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6E8W
- Type
- protein
- Length
- 153 residues
- Chains
- 3
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Envelope glycoprotein GP160
- UniProt
- Q74849
- Pockets
- 2 · best druggability 0.73
Structure
solution nmr · 1 distinct chain · 69% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | Envelope glycoprotein GP160 | protein | 51 | 69% helix, 0% strand | Q74849 |
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1041 | 0.73 | 0.76 | 73 | empty |
| 2 | 350 | 0.72 | 0.84 | 33 | empty |
Interfaces
3 interfaces between chains.
- B–C · 635 Ų buried · 2 hydrogen bonds · protein-protein
- A–B · 629 Ų buried · 2 hydrogen bonds · protein-protein
- A–C · 594 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
- 6E8W · MPER-TM Domain of HIV-1 envelope glycoprotein (Env) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q74849
- Elsewhere: RCSB PDB 6E8W · PDBe 6E8W · UniProt Q74849
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.