Research workbench
Crystal structure of a bacterial homolog to human lysosomal transporter, spinster, in inward-facing and occupied conformation
Analyse Crystal structure of a bacterial homolog to human lysosomal transporter… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6E8J
- Type
- protein
- Length
- 465 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Major facilitator family transporter
- UniProt
- Q0C3L7
- Pockets
- 5 · best druggability 0.81
Structure
x-ray diffraction · 1 distinct chain · 78% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Major facilitator family transporter | protein | 465 | 78% helix, 0% strand | Q0C3L7 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1019 | 0.81 | 0.82 | 74 | empty |
| 2 | 87 | 0.39 | 0.77 | 17 | empty |
| 3 | 58 | 0.37 | 0.79 | 18 | empty |
| 4 | 57 | 0.32 | 0.76 | 11 | empty |
| 5 | 76 | 0.29 | 0.72 | 13 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 6E8J · Crystal Structure of A Bacterial Homolog to Human Lysosomal Transporter, Spinster, in… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q0C3L7
- Elsewhere: RCSB PDB 6E8J · PDBe 6E8J · UniProt Q0C3L7
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.