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Crystal structure of the homeo-prospero domain of D. melanogaster prospero

Analyse Crystal structure of the homeo-prospero domain of D. melanogaster prospero in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1MIJ
Type: protein
Length: 139 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein prospero
UniProt: P29617
Pockets: 1 · best druggability 0.32

Structure

x-ray diffraction · 1 distinct chain · 66% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein prospero	protein	139	66% helix, 0% strand	P29617

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	83	0.32	0.73	14	empty

Modifications

Observed in the structure: 5 modified (engineered).

Compared structures

1MIJ · Crystal Structure of the Homeo-prospero Domain of D. melanogaster Prospero · the same entry in another collection · chain A against A, TM-score 1.00
P29617 · AlphaFold monomer V2.0 prediction for homeobox protein prospero (P29617) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P29617
Elsewhere: RCSB PDB 1MIJ · PDBe 1MIJ · UniProt P29617

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