Crystal structure of the heterocomplex between human keratin 1 coil 1B containing S233L mutation and wild-type human keratin 10 coil 1B

Structure

x-ray diffraction · 2 distinct chains · 97% helix, 0% strand (DSSP).

Ligands and binding sites

• SO4 · Sulfate ion · ion · 4 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–B · 2939 Ų buried · 9 hydrogen bonds · protein-protein

Compared structures

• 6E2J · Crystal structure of the heterocomplex between human keratin 1 coil 1B containing S233L… · the same entry in another collection · chain A against A, TM-score 1.00
• P04264 · AlphaFold monomer V2.0 prediction for keratin, type II cytoskeletal 1 (P04264) · a predicted model of the same protein · chain A against A, TM-score 0.89
• P13645 · AlphaFold monomer V2.0 prediction for keratin, type I cytoskeletal 10 (P13645) · a predicted model of the same protein · chain B against A, TM-score 0.80

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P04264
• Every structure of UniProt P13645
• Elsewhere: RCSB PDB 6E2J · PDBe 6E2J · UniProt P04264 · UniProt P13645