Research workbench
AFTMEM16 reconstituted in nanodiscs in the absence of CA2+
Analyse AFTMEM16 reconstituted in nanodiscs in the absence of CA2+ in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6DZ7
- Type
- protein
- Length
- 1,148 residues
- Chains
- 2
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Plasma membrane channel protein (AQY1), putative
- UniProt
- Q4WA18
- Pockets
- 20 · best druggability 0.80
Structure
electron microscopy · 1 distinct chain · 63% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B, A | Plasma membrane channel protein (AQY1), putative | protein | 574 | 63% helix, 2% strand | Q4WA18 |
Pockets
20 pockets found on a 1 Å grid, 13 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1026 | 0.80 | 0.81 | 99 | empty |
| 2 | 1042 | 0.79 | 0.81 | 97 | empty |
| 3 | 498 | 0.75 | 0.83 | 57 | empty |
| 4 | 633 | 0.75 | 0.81 | 74 | empty |
| 5 | 678 | 0.70 | 0.78 | 69 | empty |
Interfaces
1 interface between chains.
- B–A · 2891 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
- 6DZ7 · afTMEM16 reconstituted in nanodiscs in the absence of Ca2+ · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q4WA18
- Elsewhere: RCSB PDB 6DZ7 · PDBe 6DZ7 · UniProt Q4WA18
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