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Crystal structure of chalcone synthase from selaginella moellendorffii - hydrogen peroxide treated

Analyse Crystal structure of chalcone synthase from selaginella moellendorffii… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6DXF
Type: protein
Length: 757 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Chalcone synthase
UniProt: D8S128
Pockets: 7 · best druggability 0.79

Structure

x-ray diffraction · 2 distinct chains · 44% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Chalcone synthase	protein	378	44% helix, 24% strand	D8S128
B	Chalcone synthase	protein	379	44% helix, 23% strand	D8S128

Pockets

7 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	405	0.79	0.87	57	empty
2	405	0.78	0.87	58	empty
3	66	0.74	0.99	21	empty
4	58	0.71	0.98	21	empty
5	199	0.54	0.78	39	empty

Interfaces

1 interface between chains.

A–B · 2282 Å² buried · 50 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 modified (oxidation).

Compared structures

6DXF · Crystal structure of chalcone synthase from Selaginella moellendorffii - hydrogen… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt D8S128
Elsewhere: RCSB PDB 6DXF · PDBe 6DXF · UniProt D8S128

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