Research workbench
Flavobacterium johnsoniae class id ribonucleotide reductase alpha subuint
Analyse Flavobacterium johnsoniae class id ribonucleotide reductase alpha subuint in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6DQW
- Type
- protein
- Length
- 1,899 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ribonucleoside-diphosphate reductase, alpha chain
- EC
- 1.17.4.1
- UniProt
- A5FCJ4
- Pockets
- 18 · best druggability 0.65
Structure
x-ray diffraction · 4 distinct chains · 48% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ribonucleoside-diphosphate reductase, alpha chain (EC 1.17.4.1) | protein | 504 | 48% helix, 10% strand | A5FCJ4 |
| B | Ribonucleoside-diphosphate reductase, alpha chain (EC 1.17.4.1) | protein | 504 | 48% helix, 10% strand | A5FCJ4 |
| C | Ribonucleoside-diphosphate reductase, alpha chain (EC 1.17.4.1) | protein | 499 | 49% helix, 10% strand | A5FCJ4 |
| D | Ribonucleoside-diphosphate reductase, alpha chain (EC 1.17.4.1) | protein | 392 | 48% helix, 11% strand | A5FCJ4 |
Pockets
18 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 263 | 0.65 | 0.82 | 43 | empty |
| 2 | 393 | 0.64 | 0.78 | 66 | empty |
| 3 | 294 | 0.62 | 0.80 | 48 | empty |
| 4 | 249 | 0.61 | 0.80 | 23 | empty |
| 5 | 468 | 0.60 | 0.75 | 54 | empty |
Interfaces
4 interfaces between chains.
- C–D · 964 Ų buried · 2 hydrogen bonds · protein-protein
- A–B · 946 Ų buried · 4 hydrogen bonds · protein-protein
- B–D · 382 Ų buried · 1 hydrogen bond · protein-protein
- A–C · 362 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 6DQW · Flavobacterium johnsoniae class Id ribonucleotide reductase alpha subuint · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A5FCJ4
- Elsewhere: RCSB PDB 6DQW · PDBe 6DQW · UniProt A5FCJ4
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