Research workbench
Crystal structure of a heptameric sm-like protein from methanobacterium thermoautotrophicum
Analyse Crystal structure of a heptameric sm-like protein from methanobacterium… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1MGQ
- Type
- protein
- Length
- 511 residues
- Chains
- 7
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sm-like protein
- UniProt
- O26745
- Pockets
- 2 · best druggability 0.52
Structure
x-ray diffraction · 3 distinct chains · 13% helix, 57% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | Sm-like protein | protein | 74 | 11% helix, 57% strand | O26745 |
| D, E, G | Sm-like protein | protein | 73 | 11% helix, 56% strand | O26745 |
| F | Sm-like protein | protein | 70 | 17% helix, 59% strand | O26745 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 325 | 0.52 | 0.74 | 54 | empty |
| 2 | 59 | 0.38 | 0.79 | 18 | empty |
Interfaces
7 interfaces between chains.
- A–B · 925 Ų buried · 21 hydrogen bonds · protein-protein
- B–C · 904 Ų buried · 20 hydrogen bonds · protein-protein
- A–G · 880 Ų buried · 14 hydrogen bonds · protein-protein
- C–D · 880 Ų buried · 20 hydrogen bonds · protein-protein
- E–F · 864 Ų buried · 16 hydrogen bonds · protein-protein
Compared structures
- 1MGQ · Crystal structure of a heptameric sm-like protein from methanobacterium… · the same entry in another collection · chain G against G, TM-score 1.00
- O26745 · AlphaFold monomer V2.0 prediction for putative snrnp sm-like protein (O26745) · a predicted model of the same protein · chain F against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O26745
- Elsewhere: RCSB PDB 1MGQ · PDBe 1MGQ · UniProt O26745
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