Research workbench
DHD131
Analyse DHD131 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6DKM
- Type
- protein
- Length
- 584 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DHD131_A; DHD131_B
- Pockets
- 6 · best druggability 0.76
Structure
x-ray diffraction · 8 distinct chains · 89% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DHD131_A | protein | 77 | 79% helix, 0% strand | — |
| B | DHD131_B | protein | 74 | 93% helix, 0% strand | — |
| C | DHD131_A | protein | 76 | 86% helix, 0% strand | — |
| D | DHD131_B | protein | 79 | 90% helix, 0% strand | — |
| E | DHD131_A | protein | 63 | 86% helix, 0% strand | — |
| F | DHD131_B | protein | 67 | 94% helix, 0% strand | — |
| G | DHD131_A | protein | 76 | 88% helix, 0% strand | — |
| H | DHD131_B | protein | 72 | 94% helix, 0% strand | — |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 958 | 0.76 | 0.79 | 72 | empty |
| 2 | 636 | 0.69 | 0.78 | 51 | empty |
| 3 | 118 | 0.47 | 0.79 | 17 | empty |
| 4 | 134 | 0.44 | 0.76 | 26 | empty |
| 5 | 66 | 0.32 | 0.74 | 15 | empty |
Interfaces
16 interfaces between chains.
- C–D · 1628 Ų buried · 15 hydrogen bonds · protein-protein
- A–B · 1571 Ų buried · 11 hydrogen bonds · protein-protein
- G–H · 1509 Ų buried · 14 hydrogen bonds · protein-protein
- E–F · 1268 Ų buried · 11 hydrogen bonds · protein-protein
- B–D · 365 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 6DKM · DHD131 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6DKM · PDBe 6DKM
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