Research workbench

Structure of arabidopsis fatty acid amide hydrolase

Analyse Structure of arabidopsis fatty acid amide hydrolase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6DHV
Type: protein
Length: 1,191 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Fatty acid amide hydrolase
EC: 3.5.1.99
UniProt: Q7XJJ7
Pockets: 11 · best druggability 0.84

Structure

x-ray diffraction · 2 distinct chains · 42% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Fatty acid amide hydrolase (EC 3.5.1.99)	protein	594	42% helix, 14% strand	Q7XJJ7
B	Fatty acid amide hydrolase (EC 3.5.1.99)	protein	597	42% helix, 14% strand	Q7XJJ7

Pockets

11 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	486	0.84	0.90	52	empty
2	583	0.84	0.89	61	empty
3	922	0.81	0.83	105	empty
4	433	0.75	0.84	56	empty
5	457	0.71	0.81	58	empty

Interfaces

1 interface between chains.

A–B · 1751 Å² buried · 15 hydrogen bonds · protein-protein

Compared structures

6DHV · Structure of Arabidopsis Fatty Acid Amide Hydrolase · the same entry in another collection · chain A against A, TM-score 1.00
Q7XJJ7 · AlphaFold monomer V2.0 prediction for fatty acid amide hydrolase (Q7XJJ7) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7XJJ7
Elsewhere: RCSB PDB 6DHV · PDBe 6DHV · UniProt Q7XJJ7

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.