Research workbench
Crystal structure of the non-structural protein 1 (NS1) effector domain W187A mutant from the A/BREVIG MISSION/1/1918 (H1N1) strain of influenza a virus
Analyse Crystal structure of the non-structural protein 1 (NS1) effector domain W187A… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6DGK
- Type
- protein
- Length
- 240 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Non-structural protein 1
- UniProt
- Q99AU3
- Pockets
- 2 · best druggability 0.41
Structure
x-ray diffraction · 1 distinct chain · 25% helix, 42% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Non-structural protein 1 | protein | 120 | 25% helix, 42% strand | Q99AU3 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 95 | 0.41 | 0.78 | 20 | empty |
| 2 | 91 | 0.40 | 0.77 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 690 Ų buried · 8 hydrogen bonds · protein-protein
Compared structures
- 6DGK · Crystal Structure of the Non-Structural Protein 1 (NS1) effector domain W187A mutant from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99AU3
- Elsewhere: RCSB PDB 6DGK · PDBe 6DGK · UniProt Q99AU3
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.