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Crystal structure of the C-terminus of homo sapiens SPIN90 (SH3- protein interacting with nck), residues 306-722

Analyse Crystal structure of the C-terminus of homo sapiens SPIN90 (SH3- protein… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6DEE
Type: protein
Length: 382 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nck-interacting protein with SH3 domain
UniProt: Q9NZQ3
Pockets: 3 · best druggability 0.67

Structure

x-ray diffraction · 1 distinct chain · 69% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nck-interacting protein with SH3 domain	protein	382	69% helix, 0% strand	Q9NZQ3

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	307	0.67	0.82	47	empty
2	85	0.60	0.88	21	empty
3	138	0.49	0.79	32	empty

Compared structures

6DEE · Crystal structure of the C-terminus of Homo sapiens SPIN90 (SH3-protein interacting with… · the same entry in another collection · chain A against A, TM-score 1.00
Q9NZQ3 · AlphaFold monomer V2.0 prediction for nck-interacting protein with SH3 domain (Q9NZQ3) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

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Every structure of UniProt Q9NZQ3
Elsewhere: RCSB PDB 6DEE · PDBe 6DEE · UniProt Q9NZQ3

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