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Apo structure of bacteroides uniformis beta-glucuronidase 1

Analyse Apo structure of bacteroides uniformis beta-glucuronidase 1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6D1N
Type: protein
Length: 1,158 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Beta-GALACTOSIDASE/BETA-glucuronidase
EC: 3.2.1.31
UniProt: A0A174CQK8
Ligands: CL
Pockets: 14 · best druggability 0.75

Structure

x-ray diffraction · 1 distinct chain · 20% helix, 33% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Beta-GALACTOSIDASE/BETA-glucuronidase (EC 3.2.1.31)	protein	579	20% helix, 33% strand	A0A174CQK8

Ligands and binding sites

CL · Chloride ion · ion · 2 copies · chains A, B
GOL · Glycerol · additive · 11 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

14 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	842	0.75	0.79	60	GOL
2	775	0.74	0.79	74	empty
3	691	0.72	0.79	67	empty
4	129	0.64	0.87	26	GOL
5	124	0.64	0.87	25	GOL

Interfaces

1 interface between chains.

A–B · 1214 Å² buried · 17 hydrogen bonds · protein-protein

Compared structures

6D1N · Apo structure of Bacteroides uniformis Beta-glucuronidase 1 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A174CQK8
Elsewhere: RCSB PDB 6D1N · PDBe 6D1N · UniProt A0A174CQK8

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