Research workbench
Cryoem structure of human enterovirus D68 emptied particle (pH 5.5 and 33 degrees celsius)
Analyse Cryoem structure of human enterovirus D68 emptied particle (pH 5.5 and 33… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6CSH
- Type
- protein
- Length
- 649 residues
- Chains
- 3
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Viral protein 1; Viral protein 3; Viral protein 2
- UniProt
- A0A097BW12, A0A1I9KXX3
- Pockets
- 6 · best druggability 0.70
Structure
electron microscopy · 3 distinct chains · 11% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Viral protein 1 | protein | 202 | 11% helix, 41% strand | A0A097BW12 |
| B | Viral protein 3 | protein | 232 | 9% helix, 31% strand | A0A097BW12 |
| C | Viral protein 2 | protein | 215 | 12% helix, 34% strand | A0A1I9KXX3 |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 268 | 0.70 | 0.85 | 27 | empty |
| 2 | 91 | 0.41 | 0.78 | 20 | empty |
| 3 | 98 | 0.37 | 0.75 | 16 | empty |
| 4 | 101 | 0.36 | 0.75 | 20 | empty |
| 5 | 83 | 0.34 | 0.75 | 18 | empty |
Interfaces
3 interfaces between chains.
- A–B · 2534 Ų buried · 35 hydrogen bonds · protein-protein
- A–C · 1713 Ų buried · 38 hydrogen bonds · protein-protein
- B–C · 1693 Ų buried · 15 hydrogen bonds · protein-protein
Compared structures
- 6CSH · CryoEM structure of human enterovirus D68 emptied particle (pH 5.5 and 33 degrees Celsius) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A097BW12
- Every structure of UniProt A0A1I9KXX3
- Elsewhere: RCSB PDB 6CSH · PDBe 6CSH · UniProt A0A097BW12 · UniProt A0A1I9KXX3
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.