Research workbench
Cryoem structure of human enterovirus D68 abortive product 2 (pH 7.2 and 4 degrees celsius)
Analyse Cryoem structure of human enterovirus D68 abortive product 2 (pH 7.2 and 4… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6CS5
- Type
- protein
- Length
- 720 residues
- Chains
- 3
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Viral protein 1; Viral protein 3; Viral protein 2
- UniProt
- A0A097BW12, A0A1I9KXX3
- Pockets
- 10 · best druggability 0.65
Structure
electron microscopy · 3 distinct chains · 8% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Viral protein 1 | protein | 243 | 5% helix, 35% strand | A0A097BW12 |
| B | Viral protein 3 | protein | 247 | 9% helix, 29% strand | A0A097BW12 |
| C | Viral protein 2 | protein | 230 | 11% helix, 32% strand | A0A1I9KXX3 |
Pockets
10 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 186 | 0.65 | 0.85 | 31 | empty |
| 2 | 192 | 0.48 | 0.76 | 33 | empty |
| 3 | 122 | 0.37 | 0.73 | 17 | empty |
| 4 | 77 | 0.36 | 0.76 | 13 | empty |
| 5 | 87 | 0.36 | 0.75 | 18 | empty |
Interfaces
3 interfaces between chains.
- A–B · 3926 Ų buried · 63 hydrogen bonds · protein-protein
- A–C · 1851 Ų buried · 40 hydrogen bonds · protein-protein
- B–C · 1824 Ų buried · 23 hydrogen bonds · protein-protein
Compared structures
- 6CS5 · CryoEM structure of human enterovirus D68 abortive product 2 (pH 7.2 and 4 degrees… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A097BW12
- Every structure of UniProt A0A1I9KXX3
- Elsewhere: RCSB PDB 6CS5 · PDBe 6CS5 · UniProt A0A097BW12 · UniProt A0A1I9KXX3
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.