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Structure of apo GRMZM2G135359 pseudokinase

Analyse Structure of apo GRMZM2G135359 pseudokinase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
6CPY
Type
protein
Length
539 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
GRMZM2G135359 pseudokinase
UniProt
B4F901
Pockets
5 · best druggability 0.52

Structure

x-ray diffraction · 2 distinct chains · 44% helix, 15% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AGRMZM2G135359 pseudokinaseprotein27745% helix, 15% strandB4F901
BGRMZM2G135359 pseudokinaseprotein26242% helix, 15% strandB4F901

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12260.520.7627empty
21720.480.7623empty
3780.380.7719empty
4550.340.7813empty
5570.300.7513empty

Interfaces

1 interface between chains.

  • A–B · 217 Ų buried · 0 hydrogen bonds · protein-protein

Compared structures

  • 6CPY · Structure of apo GRMZM2G135359 pseudokinase · the same entry in another collection · chain A against A, TM-score 1.00

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