Research workbench

Monomeric lys-49 phospholipase A2 homologue purified from ag

Analyse Monomeric lys-49 phospholipase A2 homologue purified from ag in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1MC2
Type: protein
Length: 122 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Acutohaemonlysin
UniProt: O57385
Pockets: 1 · best druggability 0.46

Structure

x-ray diffraction · 1 distinct chain · 48% helix, 7% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Acutohaemonlysin	protein	122	48% helix, 7% strand	O57385

Ligands and binding sites

IPA · Isopropyl alcohol · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	117	0.46	0.78	20	IPA

Modifications

Observed in the structure: 7 disulfide (disulfide).

Compared structures

1MC2 · monomeric LYS-49 phospholipase A2 homologue purified from AG · the same entry in another collection · chain A against A, TM-score 1.00
O57385 · AlphaFold monomer V2.0 prediction for basic phospholipase A2 homolog acutohaemolysin… · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O57385
Elsewhere: RCSB PDB 1MC2 · PDBe 1MC2 · UniProt O57385

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.