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Solution structure of an isolated antibody vl domain

Analyse Solution structure of an isolated antibody vl domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1MAK
Type: protein
Length: 113 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: IGG2A-kappa 26-10 fv (light chain)
UniProt: P01631
Pockets: 1 · best druggability 0.30

Structure

solution nmr · 1 distinct chain · 0% helix, 43% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	IGG2A-kappa 26-10 fv (light chain)	protein	113	0% helix, 43% strand	P01631

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	54	0.30	0.76	17	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

1MAK · Solution structure of an isolated antibody vl domain · the same entry in another collection · chain A against A, TM-score 1.00
P01631 · AlphaFold monomer V2.0 prediction for ig kappa chain V-II region 26-10 (P01631) · a predicted model of the same protein · chain A against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P01631
Elsewhere: RCSB PDB 1MAK · PDBe 1MAK · UniProt P01631

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