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Cricket paralysis virus rnai suppressor protein crpv-1A

Analyse Cricket paralysis virus rnai suppressor protein crpv-1A in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
6C3R
Type
protein
Length
282 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Cricket paralysis virus 1A protein
EC
3.4.22.-, 2.7.7.48
UniProt
Q9IJX4
Pockets
3 · best druggability 0.63

Structure

x-ray diffraction · 1 distinct chain · 48% helix, 11% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A, BCricket paralysis virus 1A protein (EC 3.4.22.-, 2.7.7.48)protein14148% helix, 11% strandQ9IJX4

Pockets

3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11390.630.8627empty
24230.620.7638empty
31020.520.8322empty

Interfaces

1 interface between chains.

  • A–B · 1353 Ų buried · 16 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 5 disulfide (disulfide).

Compared structures

  • 6C3R · Cricket paralysis virus RNAi suppressor protein CrPV-1A · the same entry in another collection · chain A against A, TM-score 1.00

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